E1415 - Jet Lag Superdrug, 25% Dementia Drop, Coffee Brain Aging, Kratom Shakeup

This episode covers: 

• Mic-628 Could Reset Your Body Clock and Cut Jet Lag in Half 

A new circadian drug candidate, Mic-628, has demonstrated the ability to shift the body’s internal clock and significantly reduce jet-lag recovery time in early human studies. In controlled simulations, participants experienced faster realignment of their sleep-wake cycles and improved daytime performance compared to standard approaches like melatonin and light timing alone. Dave explains how this compound targets a core clock pathway, why eastbound travel is biologically harder than westbound, and how pharmacologic chronotherapy could become a serious...