The a16z Show

David Ulevitch speaks with Chris Power, founder and CEO at Hadrian, and Vice Admiral Robert Gaucher, the Pentagon's first direct reporting portfolio manager for submarines, at the opening of Hadrian's Factory Four in Cherokee, Alabama. They discuss the state of America's submarine industrial base, why the Navy now needs more than five times the manufacturing capacity it had a decade ago, and how software-driven factories and a new workforce can close the gap.   Resources: Follow Chris Power on LinkedIn: https://www.linkedin.com/in/powerc/ Follow VADM Robert Gaucher on LinkedIn: h...

Erin Price-Wright speaks with Adam Warmoth, founder and CEO of Chariot Defense, and Alex Miller, CTO of the U.S. Army, about the power crisis at the heart of modern military operations. As the battlefield becomes more distributed and electronics-heavy, the Army's legacy power infrastructure, built around diesel generators and lead-acid batteries, is struggling to keep up. They examine how commercial breakthroughs in EV and aviation technology are being adapted for the front line, why fuel convoys are a military liability, and how procurement reform is letting startups get hardware into soldiers' hands faster than ever.   <p...

Bridgit Mendler, Co-founder and CEO of Northwood, joins a16z’s Erik Torenberg to discuss the critical but overlooked bottleneck in space: ground infrastructure. Northwood is building the systems that connect satellites back to Earth, enabling faster, more scalable space missions. They cover Bridgit’s unconventional path to founding a space company, why vertical integration matters in hard tech, and how modern ground networks could unlock the next wave of innovation in the space economy, from national security to new commercial applications.   Resources: Follow Bridgit on X: https://x.com/bridgitmendler <p...

In this conversation, Shyam Sankar, chief technology officer at Palantir Technologies, discusses his new book Mobilize, his commission in the U.S. Army, and why he believes the most important thing America can do right now is inspire its latent heretics to step forward. He also breaks down how he thinks about the SaaS market under AI pressure, what the "alpha versus beta software" distinction means for which companies survive, and why he started a film production company. Stay Updated:Find a16z on YouTube: YouTubeFind a16z on X<...

A new paper, “Some Simple Economics of AGI,” is making the rounds—Web3 with a16z we sat down with author Christian Catalini (MIT Crypto Economics Lab) and Eddy Lazzarin (CTO of a16z crypto), in conversation with Robert Hackett, to unpack what AGI could mean for work and markets. EPISODE NOTES:  A hot paper — "Some Simple Economics of AGI" — has been making the rounds, so we sat down with the author, covering:  Automation vs. verification: the key economic split  Why AI agents now feel like coworkers - What's happening to junior roles and the “codifier...

Erik Torenberg sits down with Jacob Helberg to discuss AI, manufacturing, supply chains, and the new geopolitics of technology. Drawing on themes from Helberg’s book The Wires of War, they explore why hardware, industrial capacity, and secure supply chains have become central to both economic strength and national security. They also unpack what it means to “win the AI race” — from model leadership and global adoption to energy, compute, tariffs, and reindustrialization in the U.S.   Resources: Find Jacob Helberg on X: https://x.com/jacobhelberg Stay Updated:<...

Vishal Misra returns to explain his latest research on how LLMs actually work under the hood. He walks through experiments showing that transformers update their predictions in a precise, mathematically predictable way as they process new information, explains why this still doesn't mean they're conscious, and describes what's actually required for AGI: the ability to keep learning after training and the move from pattern matching to understanding cause and effect.   Resources: Follow Vishal Misra on X: https://x.com/vishalmisra  Follow Martin Casado on X: https://x.com/martin_casado   ...

In this episode, originally aired on Big Technology Podcast, Olivia Moore discusses whether AI startups can compete with the big chatbots, why American sentiment toward AI is so negative, and what she learned from giving LLMs personality tests. She also breaks down where ChatGPT, Claude, and Gemini are diverging, why Open Claw signals a new wave of agentic products, and what makes memory the most underrated feature in consumer AI.   Resources: Follow Olivia Moore on X:  https://x.com/omooretweets Follow Alex Kantrowitz on X:  https://x.com/Kantrowitz Lis...

Marc Andreessen joins David Senra on the Founders podcast for a conversation about entrepreneurship, history, and what drives some of the world’s most ambitious builders. In this conversation with David, Marc reflects on patterns he’s seen across great founders, why many of them focus relentlessly on building rather than introspection, and how technology and entrepreneurship continue to shape the future.   Resources: David Senra Website: https://www.davidsenra.com X: https://x.com/davidsenra Show notes: https://www.davidsenra.com/episode/ma... Marc...

This conversation with Emil Michael, undersecretary of defense for research and engineering and acting director of the Defense Innovation Unit, was recorded at the a16z American Dynamism Summit in Washington, D.C. Michael walks through how he inherited a department running 14 undefined technology priorities, cut them to six, and made applied AI number one. He also gives the first detailed account of why commercial AI contracts written under the previous administration created a vendor-lock crisis that put active military operations at risk.     Stay Updated:Find a16z on YouTube: Yo...

This conversation with Alex Karp, cofounder and CEO of Palantir, was recorded at the a16z American Dynamism Summit in Washington, D.C. Karp discusses the role of technology in modern warfare, Silicon Valley's obligations to national defense, and why he believes America's single greatest competitive advantage is its ability to cultivate and protect unconventional talent.     Stay Updated:Find a16z on YouTube: YouTubeFind a16z on XFind a16z on LinkedInListen to the a16z Show on SpotifyLi...

In this episode, previously aired on Cheeky Pint, Garrett Langley describes how a stolen gun in his Atlanta neighborhood led him to build Flock Safety, now deployed in more than 6,000 cities and involved in clearing over a million crimes last year. He covers how the product has evolved from license plate cameras to drones, real-time 911 integration, and an AI-powered orchestration layer for city safety.   Resources: Follow Garrett Langley on X: https://twitter.com/glangley Follow John Collison on X:   https://twitter.com/collision Listen to Cheeky Pint: https://www.you...

Anish Acharya speaks with Olivia Moore about the latest edition of the a16z Top 100 AI Apps report. They cover why ChatGPT is still 30 times bigger than Claude on web, how the three major platforms are specializing for different users, what global adoption data reveals about cultural attitudes toward AI, and why agents, memory, and voice are about to change everything.   Resources: Follow Anish Acharya on X: https://twitter.com/illscience Follow Olivia Moore on X: https://twitter.com/omooretweets Stay Updated:Find a16z on Y...

Daisy Wolf speaks with Dr. Andrew Huberman, professor of neurobiology and ophthalmology at Stanford University and host of the Huberman Lab podcast. They discuss how the pandemic sparked a consumer health revolution, the emerging peptide and GLP landscape, what the science actually says about focus drugs, and the neurotechnologies Huberman believes will let us write to our own biology within the next five years.   Resources: Follow Andrew Huberman on X: https://twitter.com/hubermanlab Follow Daisy Wolf on X: https://twitter.com/daisydwolf Stay Updated:Find a...

Alex Rampell and Erik Torenberg speak with Mike Cannon-Brookes, cofounder and CEO of Atlassian, about how to make sense of the SaaS selloff, why not all software companies face the same AI-driven risks, and how Atlassian is thinking about the shift from records to processes. They also examine the real design challenge of getting everyday users to trust and benefit from AI agents in enterprise workflows.   Resources: Follow Alex Rampell on X:  https://twitter.com/arampell Follow Erik Torenberg on X:   https://twitter.com/eriktorenberg Follow Mike Cannon-Brookes on X: h...

In this conversation, previously aired on TBPN, John Coogan and Jordi Hays speak with Ben Thompson, founder of Stratechery, about his essay "Anthropic and Alignment" and the broader collision between AI power and state power that the Anthropic–Department of War standoff revealed.   Resources: Follow Ben Thompson on X: https://twitter.com/benthompson Follow John Coogan on X: https://twitter.com/johncoogan Follow Jordi Hays on X: https://twitter.com/jordihays Follow TBPN on X: https://twitter.com/tbpn Stay Updated:Find a16...

a16z general partner Julie Yoo talks with Nikhil Buduma, CEO and cofounder of Ambience Healthcare, to discuss how AI is transforming clinical workflows. They cover the early days of deep learning, why Ambience started by running a medical practice before building a platform company, and what it takes to achieve high clinician adoption rates at major academic medical centers. They also dig into the challenge of building products when AI capabilities change every few months, the real ROI that's finally converting CFOs, and why this might be the moment to reimagine the legacy EHR stack.   <p...

On the show Long Strange Trip, Sequoia Capital partner Brian Halligan speaks with a16z’s Ben Horowitz about what separates great founder CEOs from everyone else. Ben explains why first-time founders lose confidence, defer too much to senior hires, and let decision debt paralyze their companies. They discuss where founder mode works and where people are taking it too far, why the VP of Sales is the hire founders mess up more than any other, and why Andy Grove's "constructive confrontation" matters more than most CEOs realize. Ben also shares what he's learned working with Zuckerberg, what Jensen Hu...

In this feed drop from the Internet History Podcast, host Brian McCullough speaks with Chris Dixon, general partner at a16z, about his path from 1980s hobbyist programmer to one of the most prominent venture capitalists in tech. Chris traces his career from quantitative finance to founding SiteAdvisor, cofounding Founder Collective, starting an early machine learning company, and eventually building a16z's crypto practice from the ground up. They also discuss his framework for spotting unconventional investments, the current state of crypto regulation, and why New York is becoming a serious tech hub.   Resources: <p...

Erik Torenberg, Ben Horowitz, and Marc Andreessen discuss how the media landscape has fundamentally changed and what a16z is doing about it. They cover why offense beats defense, why individuals now matter more than corporate brands, why speed wins in the new media landscape, and the difference between oral and written culture on the internet.   Resources: Follow Erik Torenberg on X: https://twitter.com/eriktorenberg Follow Ben Horowitz on X: https://twitter.com/bhorowitz Follow Marc Andreessen on X: https://twitter.com/bhorowitz Stay Updated:</p...