S3E19 - Unlocking phagocytosis―a look at advanced cancer immunology

In this inspiring episode, Dr. Felipe Gálvez-Cancino, group leader at Oxford's Center for Immuno-Oncology, walks us through his team’s groundbreaking research on macrophages, T cells, and immune regulation in solid tumors. Tracing his path from early cancer vaccine work to advanced antibody-dependent cellular phagocytosis (ADCP), Felipe shares how his team is working to reprogram tumor-associated macrophages to more efficiently eliminate cancer cells.

He explains how regulatory CD4+ T cells suppress both T cell and macrophage responses within tumors and how removing that suppression can supercharge phagocytic function. We also hear how his lab is leveraging mouse...