Superintelligence for Scientific Discovery in the Material World - Markus J. Buehler - MIT
Published: November 11, 2025
Duration: 29:41
We open Season 5 of the CDFAM podcast with a keynote presentation from the CDFAM Computational Design Symposium NYC 2025 by Markus J. Buehler, McAfee Professor of Engineering at MIT.
In this session, Buehler outlines how AI is becoming an autonomous partner in scientific discovery—capable not only of analysis but of generating new knowledge. Drawing on examples from materials science and bioengineering, he presents multi-agent AI systems designed to reason, hypothesize, and evolve—creating a framework for discovery engines that extend the boundaries of human-led research.
Buehler’s work brings together reinforcement learning, graph-based reasoning, and physic...