Emergency Medical Minute

Episode 958: Intranasal Fentanyl

Published: May 26, 2025

Duration: 1:52

Contributor: Aaron Lessen, MD
Educational Pearls:

How do we take care of kids in severe pain?

There are many non-pharmacologic options for pain (i.e. ice, elevation) as well as more conventional medication options (i.e. acetaminophen, NSAIDS) but in severe pain stronger medications might be indicated. These stronger medications include options such as IV morphine, a subdissociative dose of ketamine, as well as intranasal fentanyl. Intranasal fentanyl has many advantages: Studies have shown it might be more effective early on in controlling pain, as in the first 15-20 minutes after administration, and then becomes...